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EPIC CODE: LAB2607 Orthopoxvirus (includes Monkeypox virus) by PCR

Important Note

Use as a sensitive test to detect members of the orthopoxviruses, including monkeypox virus and vaccinia virus.

Additional Codes


ARUP:     3005716


UnityPoint Health Methodist collection and processing
UnityPoint Health Pekin collection and processing
UnityPoint Health Proctor collection and processing

Testing Performed at ARUP  



Lesion swab in Viral Transport Media (ARUP supply #12884) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.

Specimen Preparation:

Swab in Viral Transport Media (VTM): Transfer swab to viral transport media.

Storage/Transport Temperature:


Unacceptable Conditions:

Calcium alginate swab, wooden swab. Specimens without swabs


Specimen source required.

Stability (from collection to initiation)

Stability: (storage/transport temperature)

Ambient: 24 hours;

Refrigerated: 7 days;

Frozen: 1 month

Interpretive Data:

This assay does not differentiate members of the orthopoxviruses. In the United States, a detected result is most likely due to monkeypox virus or vaccinia virus. Other orthopoxviruses may be considered if appropriate. Refer to the US Centers for Disease Control and Prevention if additional confirmatory testing is needed.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.


Days Performed:    Sun-Sat

Reported:  1-3 days

Duration of Testing:

Methodology:  Qualitative Polymerase Chain Reaction

CPT:   87798